Author:
Sun Manman,Li Jinshan,Chen Weida,Wu Haijian,Yang Jianguo,Wang Zhiming
Abstract
Palladium-catalyzed [4+2] annulation of aryl and alkenyl carboxamides with 1,3-dienes via C–H functionalization is developed using air as the terminal oxidant. The method demonstrates good functional group tolerance and high stereoselectivity, affording a series of 3,4-dihydroisoquinolones and 5,6-dihydropyridinones in yields of up to 99%.
Funder
Natural Science Foundation of Zhejiang Province
Subject
Organic Chemistry,Catalysis
Cited by
22 articles.
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