Convenient One-Pot Synthesis of Allylsilanes from Enolizable Ketones
Author:
Kwan Man Lung D.1ORCID,
Challen Paul R.,
Tran Quynh D.-D.
Affiliation:
1. Department of Chemistry, John Carroll University
Abstract
A convenient one-pot synthesis of allylsilanes from enolizable methyl aryl ketones has been developed. The first step involves nucleophilic addition of the trimethylsilylmethyl group to ketones using the alkylation method developed by Ishihara with slight modification to generate the corresponding β-silylalkoxides. The second step entails addition of diisobutylaluminum chloride and heating at about 130 °C overnight to afford allylsilanes in fair yields.
Publisher
Georg Thieme Verlag KG
Subject
Organic Chemistry,Materials Science (miscellaneous),Biomaterials,Catalysis