Impact of Lockdown Measures during COVID-19 Pandemic on Pregnancy and Preterm Birth-Reference-Cited by-同舟云学术

Impact of Lockdown Measures during COVID-19 Pandemic on Pregnancy and Preterm Birth

Published:2021-11-14 Issue: Volume: Page:
ISSN:0735-1631
Container-title:American Journal of Perinatology
language:en
Short-container-title:Am J Perinatol

Author:

Alshaikh Belal¹,Cheung Po-Yin²³,Soliman Nancy⁴,Brundler Marie-Anne⁵,Yusuf Kamran¹

Affiliation:

1. Department of Pediatrics, Cumming School of Medicine, University of Calgary, Alberta, Canada

2. Department of Pediatrics, University of Alberta, Edmonton, Alberta, Canada

3. Department of Pharmacology and Surgery, University of Alberta, Edmonton, Alberta, Canada

4. Department of Obstetrics and Gynecology, University of Calgary Cumming School of Medicine, Calgary, Alberta, Canada

5. Departments of Pathology and Laboratory Medicine and Pediatrics, University of Calgary Cumming School of Medicine, Calgary, Alberta, Canada

Abstract

Objective The objective of this study is to assess the effect of the lockdown measures during the coronavirus disease 2019 (COVID-19) pandemic on pregnancy outcomes of women who were not affected by severe acute respiratory syndrome coronavirus 2 infection. Study Design We used data from the perinatal health program and neonatal databases to conduct a cohort analysis of pregnancy outcomes during the COVID-19 lockdown in the Calgary region, Canada. Rates of preterm birth were compared between the lockdown period (March 16 to June 15, 2020) and the corresponding pre-COVID period of 2015 to 2019. We also compared maternal and neonatal characteristics of preterm infants admitted to neonatal intensive care units (NICUs) in Calgary between the two periods. Findings A total of 4,357 and 24,160 live births occurred in the lockdown and corresponding pre-COVID period, respectively. There were 366 (84.0 per 1,000 live births) and 2,240 (92.7 per 1,000 live births) preterm births in the lockdown and corresponding pre-COVID period, respectively (p = 0.07). Rates of very preterm and very-low-birth-weight births were lower in the lockdown period compared with the corresponding pre-COVID period (11.0 vs. 15.6 and 9.0 vs. 14.4 per 1,000 live births, p = 0.02 and p = 0.005, respectively). There was no difference in spontaneous stillbirth between the two periods (3.7 vs. 4.1 per 1,000 live birth, p = 0.71). During the lockdown period, the likelihood of multiple births was lower (risk ratio [RR] 0.73, 95% confidence interval [CI]: 0.60–0.88), while gestational hypertension and clinical chorioamnionitis increased (RR 1.24, 95%CI: 1.10–1.40; RR 1.33, 95%CI 1.10–1.61, respectively). Conclusion Observed rates of very preterm and very-low-birth-weight births decreased during the COVID-19 lockdown. Pregnant women who delivered during the lockdown period were diagnosed with gestational hypertension and chorioamnionitis more frequently than mothers in the corresponding pre-COVID period. Key Points

Publisher

Georg Thieme Verlag KG

Subject

Obstetrics and Gynecology,Pediatrics, Perinatology and Child Health

Link

http://www.thieme-connect.de/products/ejournals/pdf/10.1055/s-0041-1739357.pdf

Reference38 articles.

1. Global, regional, and national causes of under-5 mortality in 2000-15: an updated systematic analysis with implications for the Sustainable Development Goals;L Liu;Lancet,2016

2. National, regional, and worldwide estimates of preterm birth rates in the year 2010 with time trends since 1990 for selected countries: a systematic analysis and implications;H Blencowe;Lancet,2012

3. Temporal trends in neonatal mortality and morbidity following spontaneous and clinician-initiated preterm birth in Washington State, USA: a population-based study;L L Richter;BMJ Open,2019

4. An overview of mortality and sequelae of preterm birth from infancy to adulthood;S Saigal;Lancet,2008

5. Preterm birth: long term cardiovascular and renal consequences;H Chehade;Curr Pediatr Rev,2018

Cited by 15 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Associations of COVID-19 lockdown with birth weight in China;Frontiers in Pediatrics;2024-01-22

2. Effect of the COVID-19 Pandemic on Stillbirths in Canada and the United States;Journal of Obstetrics and Gynaecology Canada;2023-12

3. COVID-19 lockdowns' impact on birth and pregnancy, and associated inequalities, within high-income countries: a systematic review and meta-analysis.;2023-11-16

4. COVID-19 pandemic and neonatal birth weight: a systematic review and meta-analysis;Public Health;2023-07

5. Changes in the rate of preterm infants during the COVID-19 pandemic Lockdown Period—data from a large tertiary German University Center;Archives of Gynecology and Obstetrics;2023-05-25