Taxonomy of Pathogen Codetection in Pediatric Case Fatalities with Adenoviral Respiratory Infection

Author:

Ninmer Emily K.1,Stewart Claire2,Sharron Matthew P.3ORCID,Ashworth Julia Noether4ORCID,Martinez-Schlurman Natalia5,Kavanagh Robert P.6,Signoff Jessica K.7ORCID,McCrory Michael C.8,Eidman Daniel B.9ORCID,Subbaswamy Anjali V.10,Shea Paul L.11ORCID,Sheram Mary Lynn12,Watson Christopher M.12ORCID,Spaeder Michael C.1ORCID

Affiliation:

1. Department of Pediatrics, Division of Pediatric Critical Care, University of Virginia School of Medicine, Charlottesville, Virginia, United States

2. Division of Critical Care Medicine, Nationwide Children's Hospital, Columbus, Ohio, United States

3. Division of Critical Care Medicine, Children's National Hospital, Washington, United States

4. Division of Pediatric Critical Care, Inova Children's Hospital, Falls Church, Virginia, United States

5. Division of Pediatric Critical Care, University of Florida School of Medicine, Gainesville, Florida, United States

6. Division of Pediatric Critical Care, Penn State College of Medicine, Hershey, Pennsylvania, United States

7. Division of Pediatric Critical Care, University of California at Davis School of Medicine, Sacramento, California, United States

8. Division of Pediatric Critical Care, Wake Forest University School of Medicine, Winston-Salem, North Carolina, United States

9. Division of Pediatric Critical Care, Yale University School of Medicine, New Haven, Connecticut, United States

10. Division of Pediatric Critical Care, University of New Mexico School of Medicine, Albuquerque, New Mexico, United States

11. Division of Pediatric Critical Care, University of North Carolina School of Medicine, Chapel Hill, North Carolina, United States

12. Department of Pediatrics, Medical College of Georgia, Augusta University, Augusta, Georgia, United States

Abstract

Abstract Objective The aim of this study was to determine the prevalence and taxonomy of pathogen codetection in pediatric case fatalities associated with adenoviral respiratory infection. Methods This retrospective case series included 107 pediatric case fatalities associated with adenoviral respiratory infection. Results We observed a high rate of pathogen codetection with broad diversity from both respiratory and nonrespiratory sources. We noted differences in codetection characteristics based on immune status; most notably that immunocompromised cases were more likely to have bacteremia and adenoviremia. Conclusions In pediatric case fatalities associated with adenoviral respiratory infection, we observed a high degree of pathogen codetection.

Publisher

Georg Thieme Verlag KG

Subject

Infectious Diseases,Pediatrics, Perinatology and Child Health

Reference10 articles.

1. Viral infections of the lower respiratory tract: old viruses, new viruses, and the role of diagnosis;A T Pavia;Clin Infect Dis,2011

2. Severe adenoviral respiratory infection in children;M C Spaeder;Intensive Care Med,2013

3. Adenovirus serotype 3 and 7 infection with acute respiratory failure in children in Taiwan, 2010-2011;C Y Lai;PLoS One,2013

4. Immunocompromised children with severe adenoviral respiratory infection;J C Tylka;Crit Care Res Pract,2016

5. Adenoviral respiratory infection-associated mortality in children: a retrospective case series;M C Spaeder;J Pediatr Intensive Care,2020

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