Concise Synthesis of Procyanidin B2 3,3′′-Digallate Using Yb(OTf)3-Mediated Self-Condensation-Reference-Cited by-同舟云学术

Concise Synthesis of Procyanidin B2 3,3′′-Digallate Using Yb(OTf)3-Mediated Self-Condensation

Published:2022-05-09 Issue:11 Volume:33 Page:1071-1074
ISSN:0936-5214
Container-title:Synlett
language:en
Short-container-title:Synlett

Author:

Tanaka Yuuri¹,Kobayashi Shu-hei¹,Kawamura Atsushi²,Makabe Hidefumi¹²,Hattori Yasunao³

Affiliation:

1. Graduate School of Science and Technology, Department of Agriculture, Shinshu University

2. Department of Biomolecular Innovation, Institute for Biomedical Sciences, Interdisciplinary Cluster for Cutting Edge Research, Shinshu University

3. Center for Instrumental Analysis, Kyoto Pharmaceutical University

Abstract

AbstractLewis acid mediated self-condensation of epicatechin gallate derivative was examined. We found that Yb(OTf)3 afforded good yield of the dimeric epicatechin gallate derivative. The condensed product was applied to the synthesis of procyanidin B2 3,3′′-digallate.

Funder

Japan Society for the Promotion of Science

Publisher

Georg Thieme Verlag KG

Subject

Organic Chemistry

Link

http://www.thieme-connect.de/products/ejournals/pdf/10.1055/s-0041-1737457.pdf

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5. Syntheses of prodelphinidin B1, B2, and B4 and their antitumor activities against human PC-3 prostate cancer cell lines

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