A Step Toward Optimizing Regenerative Medicine Principle to Combat COVID-19-Reference-Cited by-同舟云学术

A Step Toward Optimizing Regenerative Medicine Principle to Combat COVID-19

Published:2021-06-21 Issue:04 Volume:57 Page:202-213
ISSN:0379-038X
Container-title:Annals of the National Academy of Medical Sciences (India)
language:en
Short-container-title:Ann Natl Acad Med Sci

Author:

Sharma Shilpa¹^ORCID,Jeyaraman Madhan²^ORCID,Muthu Sathish³^ORCID,Anudeep Talagavadi Channaiah⁴^ORCID,Jeyaraman Naveen⁵^ORCID,Shringeri Ajay Satish⁶^ORCID,Kumar Vinodh⁷^ORCID,Somasundaram Rajeswari⁸^ORCID,Jain Rashmi⁹^ORCID,Jha Saurabh Kumar¹⁰^ORCID

Affiliation:

1. Department of Paediatric Surgery, All India Institute of Medical Sciences, New Delhi, India

2. Department of Orthopaedics, School of Medical Sciences and Research, Sharda University, Greater Noida, Uttar Pradesh, India

3. Department of Orthopaedics, Government Medical College and Hospital, Dindigul, Tamil Nadu, India

4. Department of Plastic Surgery, Topiwala National Medical College and BYL Nair Ch. Hospital, Mumbai, Maharashtra, India

5. Department of Orthopaedics, Kasturba Medical College, MAHE University, Manipal, Karnataka, India

6. Department of Orthopedics, Sri Devaraj URS Medical College, Kolar, Karnataka, India

7. Biocon Biologics, Chennai, Tamil Nadu, India

8. Department of Microbiology, PSG BioNEST, PSG TECH, Coimbatore, Tamil Nadu, India

9. School of Medical Sciences and Research, Sharda University, Greater Noida, Uttar Pradesh, India

10. Department of Biotechnology, School of Engineering and Technology, Sharda University, Greater Noida, Uttar Pradesh, India

Abstract

AbstractDrugs are currently not licensed in specific to pulverize COVID-19. On an emergency basis, vaccines were approved to prevent the further spread of COVID-19. This serves as a potential background for considering the optimization of biologics. In this context, evidence on convalescent plasma and stem cells has shown a beneficial role. Here, we have considered this as plausible therapy, and further hypothesize that their cocktails will synergistically boost the immunogenicity to relegate COVID-19. This warrants a large volume clinical trial on an emergent basis, because the sooner we establish a safe and effective cure, the better.

Publisher

Georg Thieme Verlag KG

Link

http://www.thieme-connect.de/products/ejournals/pdf/10.1055/s-0041-1731597.pdf

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