Prostate-Specific Antigen: From Promising to Disappointment Tool for Diagnosis of Chronic Renal Failure in Predialysis Patients-Reference-Cited by-同舟云学术

Prostate-Specific Antigen: From Promising to Disappointment Tool for Diagnosis of Chronic Renal Failure in Predialysis Patients

Published:2021-04-29 Issue:02 Volume:07 Page:082-084
ISSN:2454-6798
Container-title:Asian Journal of Oncology
language:en
Short-container-title:Asian Journal of Oncology

Author:

Al-Janabi Ali Abdul Hussein S¹

Affiliation:

1. Department of Microbiology, College of Medicine, University of Karbala, Karbala, Iraq

Abstract

Abstract Introduction Prostate-specific antigen (PSA) is a biomarker commonly used for detection of prostate cancer. Its viability as a marker for diagnosis of chronic renal failure (CRF) in predialysis patients was investigated. Methods Sera from 230 patients with CRF were analyzed by enzyme-linked immunosorbent assay (ELISA) for determining total PSA (tPSA) levels before hemodialysis. Results Of the patients investigated, 98.69% had a normal PSA level with a value less than 4 ng/mL. Three elderly men with both kidney failure showed a moderate elevation of PSA level. Conclusion PSA is considered a nonsignificant indicator for diagnosis of CRF.

Publisher

Georg Thieme Verlag KG

Link

http://www.thieme-connect.de/products/ejournals/pdf/10.1055/s-0041-1729346.pdf

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