Application of Metanephrine and Normetanephrine in Evaluating the Selectivity of Adrenal Vein Sampling-Reference-Cited by-同舟云学术

Application of Metanephrine and Normetanephrine in Evaluating the Selectivity of Adrenal Vein Sampling

Published:2022-03 Issue:03 Volume:54 Page:162-167
ISSN:0018-5043
Container-title:Hormone and Metabolic Research
language:en
Short-container-title:Horm Metab Res

Author:

Liu Wei¹,Zhang Jingjing¹,Yang Yaling²,Jin Yinxin¹,Li Zaizhao¹,You Liting¹,Luo Jianguang³,Su Xin¹^ORCID

Affiliation:

1. National Clinical Research Center for Metabolic Diseases, Institute of Metabolism and Endocrinology, Department of Metabolism and Endocrinology, The Second Xiangya Hospital of Central South University, Hunan, China

2. Department of Metabolism and Endocrinology, Xuhui Central Hospital, Fudan University, Shanghai, China

3. Department of Radiology, The Second Xiangya Hospital of Central South University, Changsha, Hunan, China

Abstract

AbstractThe aim of the study was to investigate the usefulness of metanephrine (MN) and normetanephrine (NMN) in bilateral simultaneous adrenal vein sampling (AVS) with and without ACTH stimulation. The study was conducted in a single referral center. Prospective recruited patients with PA were treated with AVS. The effects of cortisol, MN and NMN on selectivity catheterization were assessed and determined by lateralization. We enrolled 54 patients with PA who were treated with simultaneous bilateral AVS with ACTH. The Selectivity Index (SI) calculated by MN was higher than that calculated by other indicators (p<0.001), the catheterization success rate of MN at baseline was the same as that of cortisol after ACTH stimulation, and in lateralization diagnosis, MN was not inferior to cortisol. In conclusion, among the studied indicators, MN is the best index for determining the catheterization selectivity in AVS, especially in the absence of ACTH stimulation.

Funder

Hunan Provincial Science and Technology Department

Publisher

Georg Thieme Verlag KG

Subject

Biochemistry (medical),Clinical Biochemistry,Endocrinology,Biochemistry,General Medicine,Endocrinology, Diabetes and Metabolism

Link

http://www.thieme-connect.de/products/ejournals/pdf/10.1055/a-1756-4937.pdf

Reference24 articles.

1. Electron kebebew 11–deoxycortisol may be superior to cortisol in confirming a successful adrenal vein catheterization without cosyntropin: a pilot study;SJ S Naris Nilubol;Int J Endo Oncol,2017

2. Androstenedione and 17-alpha-hydroxyprogesterone are better indicators of adrenal vein sampling selectivity than cortisol;G Ceolotto;Hypertension,2017

3. Mass spectrometry-based adrenal and peripheral venous steroid profiling for subtyping primary aldosteronism;G Eisenhofer;Clin Chem,2016

4. Study of diurnal fluctuations of plasma methoxyamines in healthy volunteers;G Hoizey;Clin Endocrinol (Oxf),2002

5. Plasma metanephrine for assessing the selectivity of adrenal venous sampling;T Dekkers;Hypertension,2013

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