Thromboinflammation as a Driver of Venous Thromboembolism-Reference-Cited by-同舟云学术

Thromboinflammation as a Driver of Venous Thromboembolism

Published:2021-12 Issue:06 Volume:41 Page:428-432
ISSN:0720-9355
Container-title:Hämostaseologie
language:de
Short-container-title:Hamostaseologie

Author:

Gauchel Nadine¹,Krauel Krystin¹,Hamad Muataz Ali¹,Bode Christoph¹,Duerschmied Daniel¹

Affiliation:

1. Department of Cardiology and Angiology I, University Heart Center Freiburg—Bad Krozingen, Faculty of Medicine, University of Freiburg, Freiburg, Germany

Abstract

AbstractThrombus formation has been identified as an integral part in innate immunity, termed immunothrombosis. Activation of host defense systems is known to result in a procoagulant environment. In this system, cellular players as well as soluble mediators interact with each other and their dysregulation can lead to the pathological process of thromboinflammation. These mechanisms have been under intensified investigation during the COVID-19 pandemic. In this review, we focus on the underlying mechanisms leading to thromboinflammation as one trigger of venous thromboembolism.

Funder

Deutsche Forschungsgemeinschaft

Publisher

Georg Thieme Verlag KG

Subject

Hematology

Link

http://www.thieme-connect.de/products/ejournals/pdf/10.1055/a-1661-0257.pdf

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