Affiliation:
1. Department of Ophthalmology, Guangxi Medical University First Affiliated Hospital, Nanning, China
Abstract
Abstract
Background To report the clinical effect of oral voriconazole only as a treatment for fungal keratitis.
History and Signs Three patients (1 female and 2 males) with culture-proven fungal keratitis (1 Mucoraceae, 1 Aspergillus, 1 Fusarium) were included in this study. The patients were treated with oral voriconazole 200 mg twice daily to observe the clinical response in the treatment of fungal keratitis.
Therapy and Outcome The mean age of the patients was 51 years and the average treatment duration was 6 weeks. The corneal inflammation in these three patients was eliminated by oral voriconazole only.
Conclusions This is the first reported case of oral voriconazole only as a treatment for fungal keratitis. We found that oral voriconazole has a significant clinical effect on the treatment of fungal keratitis.
Funder
Natural Science Foundation of Guangxi Zhuang Autonomous Region
National Natural Science Foundation of China
Cited by
3 articles.
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