Manganese-Catalyzed Synthesis of Imines from Primary Alcohols and (Hetero)Aromatic Amines

Author:

Raydan Daniel12,Friães Sofia2,Royo Beatriz2,Marques M. Manuel B.1ORCID,Viduedo Nuno1,Santos A. Sofia1,Gomes Clara S. B.134ORCID

Affiliation:

1. LAQV-REQUIMTE, Departamento de Química, NOVA School of Science and Technology, Universidade Nova de Lisboa, Campus de Caparica

2. ITQB NOVA, Instituto de Tecnologia Química e Biológica António Xavier, Universidade Nova de Lisboa

3. UCIBIO – Applied Molecular Biosciences Unit, Department of Chemistry, School of Science and Technology NOVA University Lisbon

4. Associate Laboratory i4HB - Institute for Health and Bioeconomy, School of Science and Technology, NOVA University Lisbon

Abstract

AbstractHerein, we describe the synthesis of a wide variety of imines through oxidative coupling of alcohols and aromatic amines catalyzed by Mn complexes bearing N^N triazole ligands. A wide variety of imines in excellent yields (up to 99%) have been prepared. Mn-based catalysts proved to be highly efficient and versatile, allowing for the first time the preparation of several imines containing N-based heterocycles.

Funder

Fundação para a Ciência e a Tecnologia

Laboratório Associado para a Química Verde

Ministério da Ciência, Tecnologia e Ensino Superior

Applied Molecular Biosciences Unit

Fundação para a Ciência e Tecnologia

Publisher

Georg Thieme Verlag KG

Subject

Organic Chemistry

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