Affiliation:
1. Department of Organic and Inorganic Chemistry, University of Oviedo
2. LAQV-REQUIMTE & Department of Chemistry, University of Aveiro
Abstract
AbstractThe potential of the Heck reaction for the C-glycosylation of phenolic compounds was explored. An efficient and general methodology for the synthesis of C-glycosylated phenolic compounds based on the Heck coupling of halogenated phenolic derivatives (chromones, 2-styrylchromones, and xanthones) and sugar alkenes was developed. The protocol was applied to the preparation of previously unreported C-glycosylated 2-styrylchromones and xanthones of potential biological relevance.
Funder
Fundação para a Ciência e a Tecnologia
Fourth Framework Programme
Spanish National Plan for Scientific and Technical Research and Innovation
Portugal 2020
Principado de Asturias
Ministerio de Asuntos Económicos y Transformación Digital
Subject
Organic Chemistry,Catalysis