Recommendations of the AGG (Section Maternal Disease) for Myasthenia Gravis in Pregnancy

Author:

Kühnert Maritta1,Schmidt Markus2,Kuschel Bettina3,Schäfer-Graf Ute Margaretha4

Affiliation:

1. Obstetrics, UFK Marburg, Marburg, Germany

2. Gynecology & Obstetrics, Sana Kliniken Duisburg GmbH, Duisburg, Germany

3. Frauenklinik und Poliklinik, Klinikum rechts der Isar, Technische Universität München, München, Germany

4. Perinatalzentrum, Klinik für Gynäkologie und Geburtshilfe, Berlin, Germany

Abstract

AbstractMyasthenia gravis is an autoimmune disease with a range of clinical presentations which manifest as combinations of weakness of the ocular, bulbar, and respiratory muscle groups and muscles of the extremities. Young women of reproductive age are most commonly affected. Preconception planning, the impact of pregnancy, prepartum management, drug therapy in pregnancy, myasthenic and cholinergic crises, fetal monitoring, peripartum management including analgesia and anesthesia during labor and cesarean section as well as neonatal management and neonatal myasthenia gravis are described here and the appropriate recommendations are given.

Publisher

Georg Thieme Verlag KG

Subject

Maternity and Midwifery,Obstetrics and Gynaecology

Reference11 articles.

1. Myasthenia gravis and pregnancy;M Varner;Clin Obstet Gynecol,2013

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3. International consensus guidance for management of myasthenia gravis: Executive summary;D B Sanders;Neurology,2016

4. Pregnancy and myasthenia gravis;J M Massey;Continuum (Minneap Minn),2014

5. Myasthenia in pregnancy: best practice guidelines from a U.K. multispecialty working group;F Norwood;J Neurol Neurosurg Psychiatry,2014

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