Affiliation:
1. Department of Chemistry, Indian Institute of Technology (BHU)
2. Department of Chemistry, Pondicherry University
Abstract
Abstract1,4-Conjugate addition of arylboronic acids to the glycal enones delivered 2-deoxy-α-aryl-C-glycosides in good yields. The reaction was catalyzed by palladium acetate in the presence of trifluoroacetic acid and 1,10-phenanthroline. A wide range of glycal enones derived from d-glucal, d-galactal, and d-rhamnal participated in the coupling reaction with different arylboronic acids smoothly. Different protecting groups including benzyl, acetyl, pivaloyl, and benzoyl were compatible under optimized conditions.
Funder
Science and Engineering Research Board
Subject
Organic Chemistry,Catalysis