Iron-Mediated Radical Nitrohalogenation Reactions of Enynes with tert-Butyl Nitrite-Reference-Cited by-同舟云学术

Iron-Mediated Radical Nitrohalogenation Reactions of Enynes with tert-Butyl Nitrite

Published:2021-05-28 Issue:12 Volume:32 Page:1192-1196
ISSN:0936-5214
Container-title:Synlett
language:en
Short-container-title:Synlett

Author:

Ren Yingming¹,Ge Yaxin¹,Yan Qinqin¹,Tian Yunfei²,Li Zejiang¹^ORCID,Wu Jilai¹,Yang Yujie¹,Li Lijun¹

Affiliation:

1. Key Laboratory of Medicinal Chemistry and Molecular Diagnosis of the Ministry of Education, College of Chemistry and Environmental Science, Key Laboratory of Chemical Biology of Hebei Province, Hebei University

2. College of Chemistry and Chemical Engineering, and Henan Key Laboratory of Function-Oriented Porous Materials, Luoyang Normal University

Abstract

AbstractA radical nitrohalogenation/cyclization of various enynes with tert-butyl nitrite has been developed that conveniently introduces useful nitro and halo groups into organic compounds. Some control experiments were performed to elucidate the mechanism. Further functional transformations proceeded well in this reaction system.

Funder

National Natural Science Foundation of China

Natural Science Foundation of Hebei Province

Department of Education of Hebei Province

National College Students Innovation and Entrepreneurship Training Program

Natural Science Foundation of Henan Province

Publisher

Georg Thieme Verlag KG

Subject

Organic Chemistry

Link

http://www.thieme-connect.de/products/ejournals/pdf/10.1055/a-1520-2192.pdf