Affiliation:
1. School of Chemistry and Materials Engineering, Liupanshui Normal University
2. Guizhou Key Laboratory of Coal Clean Utilization
Abstract
AbstractBy employing either borrowing hydrogen or transfer hydrogenation strategy, two straightforward [Ru(p-cymene)Cl2]2-catalyzed methods for regioselective synthesis of C3-alkylated indoles have been developed, utilizing alcohols as H atom donors or alkylating agents. The developed catalytic system could accommodate a broad substrate scope including primary/secondary aliphatic alcohols and substituted indoles, and in most cases providing good yields. Notable features of the developed system include high-activity, easy operation, and air atmosphere.
Funder
National Natural Science Foundation of China
Liupanshui Normal University
Subject
Organic Chemistry,Catalysis
Cited by
4 articles.
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