Value of PET imaging for radiation therapy

Author:

Lapa Constantin1,Nestle Ursula234,Albert Nathalie L.5,Baues Christian6,Beer Ambros7,Buck Andreas8,Budach Volker9,Bütof Rebecca1011,Combs Stephanie E.121314,Derlin Thorsten15,Eiber Matthias16,Fendler Wolfgang P.17,Furth Christian18,Gani Cihan1920,Gkika Eleni2,Grosu Anca L.23,Henkenberens Christoph21,Ilhan Harun5,Löck Steffen1011,Marnitz-Schulze Simone6,Miederer Matthias22,Mix Michael23,Nicolay Nils H.23,Niyazi Maximilian512,Pöttgen Christoph24,Rödel Claus M.2526,Schatka Imke18,Schwarzenboeck Sarah M.27,Todica Andrei S.5,Weber Wolfgang16,Wegen Simone6,Wiegel Thomas28,Zamboglou Constantinos23,Zips Daniel1920,Zöphel Klaus1129303132,Zschaeck Sebastian33,Thorwarth Daniela1934,Troost Esther G.C.1011293035ORCID,

Affiliation:

1. Nuclear Medicine, Medical Faculty, University of Augsburg, Augsburg, Germany

2. Department of Radiation Oncology, Faculty of Medicine, University Medical Center Freiburg, Freiburg, Germany

3. German Cancer Consortium (DKTK), Partner Site Freiburg, Freiburg, Germany

4. Department of Radiation Oncology, Kliniken Maria Hilf, Mönchengladbach, Germany

5. Department of Nuclear Medicine, University Hospital, LMU Munich, Munich, Germany

6. Department of Radiation Oncology, Cyberknife and Radiotherapy, Medical Faculty, University Hospital Cologne, Cologne, Germany

7. Department of Nuclear Medicine, Ulm University Hospital, Ulm, Germany

8. Department of Nuclear Medicine, University Hospital Würzburg, Würzburg, Germany

9. Department of Radiation Oncology, Charité-Universitätsmedizin Berlin, Campus Virchow-Klinikum, Berlin, Germany

10. Department of Radiotherapy and Radiation Oncology, Faculty of Medicine and University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany

11. OncoRay – National Center for Radiation Research in Oncology, Faculty of Medicine and University Hospital Carl Gustav Carus, Technische Universität Dresden, Helmholtz-Zentrum Dresden-Rossendorf, Dresden, Germany

12. German Cancer Consortium (DKTK), Partner Site Munich, Munich, Germany

13. Department of Radiation Oncology, Technical University of Munich (TUM), Klinikum rechts der Isar, Munich, Germany

14. Department of Radiation Sciences (DRS), Institute of Radiation Medicine (IRM), Neuherberg, Germany

15. Department of Nuclear Medicine, Hannover Medical School, Germany

16. Department of Nuclear Medicine, Technical University of Munich (TUM), Klinikum rechts der Isar, Munich, Germany

17. Department of Nuclear Medicine, University of Duisburg-Essen and German Cancer Consortium (DKTK)-University Hospital Essen, Essen, Germany

18. Department of Nuclear Medicine, Charité-Universitätsmedizin Berlin, Freie Universität Berlin, Humboldt-Universität zu Berlin, Berlin Institute of Health, Berlin, Germany

19. German Cancer Consortium (DKTK), Partner Site Tübingen, and German Cancer Research Center (DKFZ), Heidelberg, Germany

20. Department of Radiation Oncology, University of Tübingen, Tübingen, Germany

21. Department of Radiotherapy and Special Oncology, Medical School Hannover, Germany

22. Department of Nuclear Medicine, University Hospital Mainz, Mainz, Germany

23. Department of Nuclear Medicine, Faculty of Medicine, Medical Center, University of Freiburg, Freiburg, Germany

24. Department of Radiation Oncology, West German Cancer Centre, University of Duisburg-Essen, Essen, Germany

25. German Cancer Consortium (DKTK), Partner Site Frankfurt, and German Cancer Research Center (DKFZ), Heidelberg, Germany

26. Department of Radiotherapy and Oncology, Goethe University Frankfurt, Frankfurt, Germany

27. Department of Nuclear Medicine, Rostock University Medical Centre, Rostock, Germany

28. Department of Radiation Oncology, Ulm University Hospital, Ulm, Germany

29. National Center for Tumor Diseases (NCT), Partner Site Dresden, Germany: German Cancer Research Center (DKFZ), Heidelberg, Germany; Faculty of Medicine and University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany; Helmholtz Association/Helmholtz-Zentrum Dresden-Rossendorf (HZDR), Dresden, Germany

30. German Cancer Consortium (DKTK), Partner Site Dresden, and German Cancer Research Center (DKFZ), Heidelberg, Germany

31. Department of Nuclear Medicine, Faculty of Medicine and University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany

32. Department of Nuclear Medicine, Klinikum Chemnitz gGmbH, Chemnitz, Germany

33. Department of Radiation Oncology, Charité-Universitätsmedizin Berlin, Charité-Universitätsmedizin Berlin, Freie Universität Berlin, Humboldt-Universität zu Berlin, Berlin Institute of Health, Berlin, Germany

34. Section for Biomedical Physics, Department of Radiation Oncology, University of Tübingen, Tübingen, Germany

35. Helmholtz-Zentrum Dresden-Rossendorf, Institute of Radiooncology – OncoRay, Dresden, Germany

Abstract

AbstractThis comprehensive review written by experts in their field gives an overview on the current status of incorporating positron emission tomography (PET) into radiation treatment planning. Moreover, it highlights ongoing studies for treatment individualisation and per-treatment tumour response monitoring for various primary tumours. Novel tracers and image analysis methods are discussed. The authors believe this contribution to be of crucial value for experts in the field as well as for policy makers deciding on the reimbursement of this powerful imaging modality.

Publisher

Georg Thieme Verlag KG

Subject

Radiology Nuclear Medicine and imaging,General Medicine

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