Copper-Catalyzed Alkylation of Quinoxalin-2(1H)-ones with Styrenes and tert-Butyl Peroxybenzoate

Abstract

AbstractA simple strategy for the synthesis of 3-substituted quinoxalin-2(1H)-ones containing ether units is proposed. The method is realized by the three-component synthesis of quinoxalin-2(1H)-ones, styrenes, and tert-butyl peroxybenzoate (TBPB). This reaction has good functional group tolerance and may involve a free-radical process.