Hepatic Sarcoidosis: Current Concepts and Treatments

Author:

Rossi Geoffrey1,Ziol Marianne2,Roulot Dominique34,Valeyre Dominique4,Mahévas Matthieu1

Affiliation:

1. Service de Médecine Interne, Centre Hospitalier Universitaire Henri-Mondor, Assistance Publique—Hôpitaux de Paris, Université Paris Est Créteil, Créteil, France

2. Service d'anatomopathologie, Centre Hospitalier Jean-Verdier, Bondy, France

3. Service d'Hépatologie, Centre Hospitalier Universitaire Avicenne, Bobigny, France

4. Service de Pneumologie, Centre Hospitalier Universitaire Avicenne, Université Sorbonne Paris Nord, APHP, Bobigny, France

Abstract

AbstractHepatic sarcoidosis is a relatively common manifestation of extrapulmonary sarcoidosis. It occurs in 20 to 30% of cases and is rarely severe. However, a cluster of patients may develop severe complications such as cirrhosis and portal hypertension. In this review, we describe the current knowledge of clinical, biological, pathological, and radiological features of liver involvement in sarcoidosis and discuss essential clues for management and treatment.

Publisher

Georg Thieme Verlag KG

Subject

Critical Care and Intensive Care Medicine,Pulmonary and Respiratory Medicine

Reference60 articles.

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