New Insights into the Pathogenesis, Risk Factors, and Treatment of Portal Vein Thrombosis in Patients with Cirrhosis-Reference-Cited by-同舟云学术

New Insights into the Pathogenesis, Risk Factors, and Treatment of Portal Vein Thrombosis in Patients with Cirrhosis

Published:2020-08-20 Issue:06 Volume:46 Page:673-681
ISSN:0094-6176
Container-title:Seminars in Thrombosis and Hemostasis
language:en
Short-container-title:Semin Thromb Hemost

Author:

Nicoară-Farcău Oana¹²,Soy Guillem²³⁴,Magaz Marta²³⁴,Baiges Anna²³⁴,Turon Fanny²³⁴,Garcia-Criado Angeles⁴⁵,Barrufet Marta⁴⁵,Burrel Marta⁴⁵,Hernández-Gea Virginia²³⁴,García-Pagán Juan Carlos²³⁴

Affiliation:

1. Department of Hepatology, Regional Institute of Gastroenterology and Hepatology “Octavian Fodor,” “Iuliu Hatieganu” University of Medicine and Pharmacy, Cluj-Napoca, Romania

2. Liver Unit, Barcelona Hepatic Hemodynamic Laboratory, Hospital Clinic, Institut d'Investigacions Biomèdiques August Pi I i Sunyer (IDIBAPS), University of Barcelona, Barcelona, Spain

3. Centro de Investigación Biomédica Red de Enfermedades Hepáticas y Digestivas (CIBEREHD), Barcelona, Spain

4. Health Care Provider of the European Reference Network on Rare Liver Disorders (ERN-Liver)

5. Department of Radiology, Hospital Clinic de Barcelona, Barcelona, Spain

Abstract

AbstractPortal vein thrombosis (PVT) is a frequent event in patients with cirrhosis regardless of etiology. Notwithstanding the commonality of the problem, the pathophysiology and risk factors for PVT in cirrhosis are largely unknown. The clinical impact of PVT in the natural history of cirrhosis is unclear, indications for PVT treatment are not well defined, and treatment recommendations are based on experts' opinion and consensus only. Therefore, this review aims to summarize current knowledge of mechanisms and risk factors for PVT development and assess the current evidence of PVT management, with a special focus on strategies of anticoagulation and transjugular intrahepatic portosystemic shunt placement.

Publisher

Georg Thieme Verlag KG

Subject

Cardiology and Cardiovascular Medicine,Hematology

Link

http://www.thieme-connect.de/products/ejournals/pdf/10.1055/s-0040-1715473.pdf

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