Gold Catalysis and Furans: A Powerful Match for Synthetic Connections

Abstract

AbstractThis review summarizes the advances made on the synthesis and functionalization of furans via gold catalysis during the period between 2016 and 2020. A separate section is dedicated to the tandem gold-catalyzed synthesis and functionalization of furans.1 Introduction2 Gold-Catalyzed Synthesis of Furans2.1 Cycloisomerizations of Alkynyl and Cumulenyl Alcohols2.2 Cycloisomerizations of Alkynyl and Allenyl Ketones2.3 Reactions with External Oxidants2.4 Miscellaneous3 Gold-Catalyzed Functionalization of Furans3.1 Cycloadditions3.2 Furan Ring Decorations3.3 Reactions Involving Furan Ring Opening4 Gold-Catalyzed Tandem Synthesis and Functionalization of Furans­4.1 Cycloisomerizations Followed by Gold-Catalyzed Cycloaddition4.2 Cycloisomerizations to a Gold 1,3- or 1,4-Dipole and Intermolecular Annulation4.3 Cycloisomerizations to a Gold Carbene and Intermolecular Trapping5 Conclusion