Population-Based Estimation of the Preterm Birth Rate in Lilongwe, Malawi: Making Every Birth Count

Author:

Antony Kathleen M.123ORCID,Kazembe Peter N.4,Pace Ryan M.15,Levison Judy1,Phiri Henry6,Chiudzu Grace6,Harris Ronald Alan1,Chirwa Rose4,Nyondo Mary4,Marko Ellina4,Chigayo Andrew4,Nanthuru Debora4,Banda Bertha4,Twyman Nicholas1,Ramin Susan M.12,Raine Susan P.1,Belfort Michael A.12,Aagaard Kjersti M.12

Affiliation:

1. Department of Obstetrics and Gynecology, Baylor College of Medicine, Houston, Texas

2. Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, Baylor College of Medicine, Houston, Texas

3. Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, University of Wisconsin-Madison, Madison, Wisconsin

4. Department of Pediatrics, Baylor College of Medicine Children's Clinical Center of Excellence, Kamuzu Central Hospital, Lilongwe, Malawi

5. Department of Immunology, University of Idaho, Moscow, Idaho

6. Department of Obstetrics and Gynecology, Kamuzu Central Hospital, Lilongwe, Malawi

Abstract

Abstract Objective The objective of this study was to perform a population-based estimation of the preterm birth (PTB) rate in regions surrounding Lilongwe, Malawi. Study Design We partnered with obstetrician specialists, community health workers, local midwives, and clinicians in a 50 km region surrounding Lilongwe, Malawi, to perform a population-based estimation of the PTB rate during the study period from December 1, 2012 to May 19, 2015. Results Of the 14,792 births captured, 19.3% of births were preterm, including preterm early neonatal deaths. Additional PTB risk factors were similarly prevalent including domestic violence, HIV, malaria, anemia, and malnutrition. Conclusion When performing a population-based estimation of the rate of PTB, including women without antenatal care and women delivering at home, the 19.3% rate of PTB is among the highest recorded globally. This is accompanied by a high rate of risk factors and comorbid conditions.

Funder

USAID/Bill & Melinda Gates Foundation Saving Lives at Birth Grand Challenges

E.W. Al Thrasher Foundation

E.W. Al Thrasher Foundation, Foundation for the National Institutes of Health

Publisher

Georg Thieme Verlag KG

Subject

Obstetrics and Gynecology,Pediatrics, Perinatology and Child Health

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