Case Series of Three Patients with Rifampicin-Induced Thrombocytopenia

Author:

M.T Chandramouli1

Affiliation:

1. Department of Pulmonary Medicine, K.S. Hegde Medical Academy, Mangalore, Karnataka, India

Abstract

AbstractLife-threatening adverse reactions of antitubercular drugs are uncommon; however, thrombocytopenia is one such rare complication encountered with rifampicin, isoniazid, ethambutol, and pyrazinamide. Rifampicin is the most effective drug and its use in the tuberculosis treatment led to the emergence of modern and effective short-course regimens. I am reporting case series of three patients with pulmonary tuberculosis presented with rifampicin-induced thrombocytopenia.

Publisher

Georg Thieme Verlag KG

Subject

Ocean Engineering

Reference12 articles.

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2. Drug-induced thrombocytopenia: a systematic review of published case reports;J N George;Ann Intern Med,1998

3. Adverse reactions to rifampicin;D J Girling;Bull World Health Organ,1979

4. Evaluation and management of drug-induced thrombocytopenia in the acutely ill patient;L D Wazny;Pharmacotherapy,2000

5. Antibodies against rifampin in patients with tuberculosis after discontinuation of daily treatment;Berardino L Di;Am Rev Respir Dis,1976

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