Dexmedetomidine Infusion as a Novel Supportive Therapy for Fluphenazine-Induced Neuroleptic Malignant Syndrome in a 10-Year-Old Boy: A Case Report and Review of Literature

Author:

Yu Caroline1,Kaul Rajat2,Ostwani Waseem3

Affiliation:

1. Department of Pediatrics, University of Toledo College of Medicine and Life Sciences, Toledo, Ohio, United States

2. Department of Pediatrics, Division of Pediatric Hospitalist Medicine, University of Toledo College of Medicine and Life Sciences, Toledo, Ohio, United States

3. Department of Pediatrics, Division of Pediatric Critical Care Medicine, University of Toledo College of Medicine and Life Sciences, Toledo, Ohio, United States

Abstract

AbstractA 10-year-old male child patient developed symptoms of neuroleptic malignant syndrome (NMS) 1 month following initiation of fluphenazine for behavioral therapeutic management. Dexmedetomidine infusion was able to adequately control the symptoms of NMS with resolution of encephalopathy. This was the first report of novel dexmedetomidine utilization for the treatment of NMS. We suggest using dexmedetomidine as an adjunctive agent to control NMS symptomatology without attendant risk of respiratory depression.

Publisher

Georg Thieme Verlag KG

Subject

Neurology (clinical),Pediatrics, Perinatology and Child Health

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