Scandium Triflate Catalyzed Nazarov Cyclization of Arylvinyl Epoxides Derived from Alkoxides and Chloro(aryl)carbenes: A Facile Access to Resveratrol-Derived Natural Products-Reference-Cited by-同舟云学术

Scandium Triflate Catalyzed Nazarov Cyclization of Arylvinyl Epoxides Derived from Alkoxides and Chloro(aryl)carbenes: A Facile Access to Resveratrol-Derived Natural Products

Published:2020-11-13 Issue:06 Volume:32 Page:605-610
ISSN:0936-5214
Container-title:Synlett
language:en
Short-container-title:Synlett

Author:

Sudhakar Gangarajula¹²^ORCID,Satish Nagam¹²

Affiliation:

1. Department of Organic Synthesis & Process Chemistry, CSIR-Indian Institute of Chemical Technology

2. Academy of Scientific and Innovative Research (AcSIR)

Abstract

AbstractThe reaction of arylvinyl alkoxides with chloro(aryl)carbenes provided the corresponding arylvinyl epoxides that underwent Nazarov cyclization in a catalytic amount of scandium triflate, providing easy access to several highly substituted indenes, including some resveratrol-derived natural products.

Funder

Science and Engineering Research Board

Publisher

Georg Thieme Verlag KG

Subject

Organic Chemistry

Link

http://www.thieme-connect.de/products/ejournals/pdf/10.1055/s-0040-1705974.pdf

Reference8 articles.

1. Chemistry and Biology of Resveratrol-Derived Natural Products

2. Inhibition of human LDL oxidation by resveratrol

3. Resveratrol improves health and survival of mice on a high-calorie diet