Copper-Catalyzed Synthesis of β- and δ-Carbolines by Double N-Arylation of Primary Amines-Reference-Cited by-同舟云学术

Copper-Catalyzed Synthesis of β- and δ-Carbolines by Double N-Arylation of Primary Amines

Published:2021-03-31 Issue:10 Volume:32 Page:1004-1008
ISSN:0936-5214
Container-title:Synlett
language:en
Short-container-title:Synlett

Author:

Hung Tran Quang¹²^ORCID,Dang Tuan Thanh³,Langer Peter⁴⁵^ORCID,Van Phuc Ban¹,Do Ha Nam³^ORCID,Quan Nguyen Minh²,Tuan Nguyen Ngoc¹,An Nguyen Quang¹,Van Tuyen Nguyen¹²,Anh Hoang Le Tuan⁶

Affiliation:

1. Institute of Chemistry, Vietnam Academy of Science and Technology

2. Graduate University of Science and Technology, Vietnam Academy of Science and Technology

3. Faculty of Chemistry, Hanoi University of Science, Vietnam National University (VNU)

4. Institut für Chemie, Universität Rostock

5. Leibniz Institut für Katalyse an der Universität Rostock e.V.

6. Center for Research and Technology Transfer, Vietnam Academy of Science and Technology

Abstract

AbstractTwo efficient and practical approaches are reported for the synthesis of β- and δ-carbolines from 3,4-dibromopyridine. The synthesis is based on site-selective Cu-catalyzed double C–N coupling reactions and subsequent annulations by twofold Pd-catalyzed C–N coupling with amines.

Funder

Vietnam National Foundation for Science and Technology Development

Publisher

Georg Thieme Verlag KG

Subject

Organic Chemistry

Link

http://www.thieme-connect.de/products/ejournals/pdf/10.1055/s-0040-1720461.pdf

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