Cerebrospinal Fluid Interaction with Cerebral Cortex during Pediatric Abusive Head Trauma

Author:

Toma Milan12ORCID,Dehesa-Baeza Alfonso2ORCID,Chan-Akaley Rosalyn3,Nguyen Paul D. H.4,Zwibel Hallie5

Affiliation:

1. Department of Osteopathic Manipulative Medicine, College of Osteopathic Medicine, New York Institute of Technology, Old Westbury Campus, Northern Boulevard, Old Westbury, New York, United States

2. Department of Mechanical Engineering, College of Engineering & Computing Sciences, New York Institute of Technology, Old Westbury Campus, Northern Boulevard, Old Westbury, New York, United States

3. Lang Research Center, NewYork-Presbyterian Queens, Flushing, New York, United States

4. Pennsylvania State College of Medicine, Hershey, Pennsylvania, United States

5. Department of Sports Medicine, College of Osteopathic Medicine, New York Institute of Technology, Westbury Campus, Northern Boulevard, Old Westbury, New York, United States

Abstract

AbstractAbusive head trauma is the leading cause of fatal brain injuries in children younger than 2 years. It is a preventable and severe form of physical child abuse often linked to the forceful shaking of an infant or toddler. Victims of abusive head trauma can suffer permanent neurological damage, resulting in developmental delay and disability. The long-term effects of abusive head trauma are difficult to diagnose and predict. In this model, we use a high-order finite element method paired with the most comprehensive and current head/brain model and next-generation smoothed particle hydrodynamics. This is one of the first fluid–structure interaction frameworks that uses fluid material properties to represent the cerebrospinal fluid (CSF) while including all major anatomical features of the brain. The interaction of CSF with the brain cortex during abusive head trauma is demonstrated during multiple shaking cycles. A comprehensive and precise model that calculates for the role of CSF in neurological trauma will be useful both in the prevention and treatment of abusive head trauma and the determination of prognosis and patient outcomes.

Funder

New York Institute of Technology and a donation from the New York Thoroughbred Horsemen's Association

Publisher

Georg Thieme Verlag KG

Subject

Neurology (clinical),Pediatrics, Perinatology and Child Health

Reference38 articles.

1. Ambroise Tardieu: the man and his work on child maltreatment a century before Kempe;J Labbé;Child Abuse Negl,2005

2. Multiple fractures in the long bones of infants suffering from chronic subdural hematoma;J Caffey;Am J Roentgenol Radium Ther,1946

3. The battered-child syndrome;C H Kempe;JAMA,1962

4. Update on abusive head trauma;A Shaahinfar;Curr Opin Pediatr,2015

5. Child maltreatment fatalities in children under 5: findings from the National Violence Death Reporting System;J Klevens;Child Abuse Negl,2010

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