Lifesaving Treatment of Aortic Valve Staphylococcus aureus Endocarditis: Daptomycin and Early Surgical Therapy

Author:

Yozgat Can Yilmaz1ORCID,Uzuner Selcuk2ORCID,Ay Yasin3ORCID,Temur Hafize Otcu4ORCID,Bursal Duramaz Burcu5ORCID,Turel Ozden5ORCID,Calim Muhittin6ORCID,Buyukpinarbasili Nur7ORCID,Yozgat Yilmaz8ORCID

Affiliation:

1. Faculty of Medicine, Bezmialem Vakif University, Istanbul, Turkey

2. Department of Pediatric Critical Care Medicine, Bezmialem Vakif University, Istanbul, Turkey

3. Department of Cardiovascular Surgery, Bezmialem Vakif University, Istanbul, Turkey

4. Department of Radiology, Bezmialem Vakif University, Istanbul, Turkey

5. Department of Pediatric Infectious Diseases, Bezmialem Vakif University, Istanbul, Turkey

6. Department of Anesthesiology and Reanimation, Bezmialem Vakif University, Istanbul, Turkey

7. Department of Pathology, Kanuni Sultan Suleyman Training and Research Hospital, Istanbul, Turkey

8. Department of Pediatric Cardiology, Bezmialem Vakif University, Istanbul, Turkey

Abstract

AbstractInfective endocarditis (IE) is an uncommon infection in children. The recommended treatment for native valve endocarditis secondary to methicillin-susceptible Staphylococcus aureus infection is antistaphylococcal penicillins such as nafcillin or oxacillin. If the initial therapy fails in IE, it can lead to catastrophic results. Nowadays, daptomycin is the best alternative antimicrobial agent to treat children with severe infections, when standard antimicrobial therapy does not yield a result. Herein, in this article, we described a case of a 16-year-old boy who had aortic valve S. aureus endocarditis with septic embolization and stroke. The patient was successfully treated only with daptomycin as well as surgical therapy in the early phase of the infection.

Publisher

Georg Thieme Verlag KG

Subject

Critical Care and Intensive Care Medicine,Pediatrics, Perinatology, and Child Health

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