A Practical and Versatile Method for the C–H Sulfenylation of Imidazo[1,2-a]pyridines

Abstract

Imidazo[1,2-a]pyridines are an important class of heterocycles that are prevalent in many bioactive small molecules. We report the direct introduction of a broad selection of aromatic, heteroaromatic, or alkyl fragments connected by a thioether group into these important heterocycles by using readily prepared thiosulfate salts.