Postinfectious T-lymphocytic enteral leiomyositis as a rare cause of chronic intestinal pseudoobstruction

Author:

Sarfo Bismark Osei1,Kopdag Hakan1,Pott Marian-Christopher2ORCID,Stiedenroth Lars1,Nahrstedt Ulf3,Schäfer Hansjörg4,von Wichert Götz5

Affiliation:

1. Schön Klinik Hamburg-Eilbek, Hamburg, Germany

2. Inselspital Universitätsspital Bern, Switzerland

3. General Surgery, Schön Klinik Hamburg-Eilbek, Hamburg, Germany

4. Pathology, Universitätsklinikum Hamburg-Eppendorf, Hamburg, Germany

5. Innere Medizin, Schön Klinik Hamburg Eilbek, Hamburg, Germany

Abstract

AbstractT-lymphocytic enteral leiomyositis (T-lel) is a rare disorder causing chronic intestinal pseudo-obstruction (CIPO), with cases predominantly being reported in the field of veterinary and pediatric medicine. Here, we present a case of T-lel-associated CIPO in an adult female, who initially presented with a paralytic ileus 2 weeks after a common gastroenteritis. The histological diagnosis was established through full-thickness bowel biopsy, exhibiting a dense lymphocytic infiltrate in the lamina muscularis of the intestinal wall. This case shows that T-lel can be a cause of chronic intestinal pseudo-obstruction not only in children but also in adults. A subsequent induction of an immunosuppressive therapy with steroids, azathioprine, and ultimately TNF-alpha-inhibiting antibodies led to a slow recovery and stable disease.

Publisher

Georg Thieme Verlag KG

Subject

Gastroenterology

Reference19 articles.

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