Evaluation of the Lung Scintiphoto as a Screening Test for Pulmonary Disease

Abstract

SummaryA method is described for the manufacture of 99mTechnetium lung scanning agent that incorporates nearly 100% of the technetium eluate and can be made from bulk solutions in about sixteen minutes. These particles were used to study the value of the lung scintiphoto as a screening procedure for pulmonary disease; comparing it with the posterior-anterior and left lateral chest roentgenogram, and the timed vital capacity. Many perfusion defects, sometimes multiple, were found to be present in lungs with normal chest roentgenograms. Perfusion abnormalities were noted in people with normal and near normal timed vital capacities. We feel that the lung scintiphoto may be a useful adjunctive screening test for pulmonary disease.