Changes in Plasminogen Activator Activity and Plasmin Inhibition in the Pig During Experimental Hypovolaemia-Reference-Cited by-同舟云学术

Changes in Plasminogen Activator Activity and Plasmin Inhibition in the Pig During Experimental Hypovolaemia

Published:1985 Issue:01 Volume:53 Page:130-133
ISSN:0340-6245
Container-title:Thrombosis and Haemostasis
language:en
Short-container-title:Thromb Haemost

Author:

Smokovitis A¹,Wagner M²,Starlinger M³,Opitz A²,Binder B R⁴

Affiliation:

1. The Department of Physiology, Veterinary Faculty, Aristotelian University of Thessaloniki, Greece

2. The First Department of Traumatology, Medical School, University of Vienna, Austria

3. The First Department of Surgery, Medical School, University of Vienna, Austria

4. The Department of Medical Physiology, Medical School, University of Vienna, Austria

Abstract

SummaryA markedly decreased plasminogen activator activity (PAA) was seen in lung, heart and kidney after experimental hypovolemia in the pig. In 2 of 12 cases, an increased PAA was found in liver and spleen. In skeletal muscle, skin, sciatic nerve and in 10 of 12 cases in liver and spleen PAA was unchanged. A slightly increased plasmin inhibition was noted only in the lung. These changes in tissue PAA were reflected by an increase in the PAA of euglobulin fractions concomitant with a decrease in antiplasmin activity in the blood samples obtained during the bleeding experiments.

Publisher

Georg Thieme Verlag KG

Subject

Hematology

Link

http://www.thieme-connect.de/products/ejournals/pdf/10.1055/s-0038-1661252.pdf

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1. Local plasminogen activator and prostacyclin-like activity after partial venous occlusion — an experimental study in the dog;Thrombosis Research;1988-07

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