Fibrinogen Valencia A New Case of Congenital Dysfibrinogenemia

Abstract

SummaryA new case of dysfibrinogenemia is described, the proband had low fibrinogen level and a moderate hyperfibrinolysis. Attention is drawn to the florid hemorrhagic picture and its early presentation.The family history showed a moderate hyperfibrinolysis.It appeared that the cause of the dysfibrinogenemia was due to a deficient polymerization of the α chains of the fibrinogen.It is not yet known if this is caused by a defective liberation of fibrinopeptides. Due to the peculiar characteristic of this case and in accordance with the international norms, we propose to call this dysfibrinogenemia “Fibrinogen Valencia.”