The Leu33/Pro Polymorphism (PIA1/PIA2 ) of the Glycoprotein IIIa (GPIIIa) Receptor Is Not Related to Myocardial Infarction in the ECTIM Study-Reference-Cited by-同舟云学术

The Leu33/Pro Polymorphism (PIA1/PIA2 ) of the Glycoprotein IIIa (GPIIIa) Receptor Is Not Related to Myocardial Infarction in the ECTIM Study

Published:1997 Issue:06 Volume:77 Page:1179-1181
ISSN:0340-6245
Container-title:Thrombosis and Haemostasis
language:en
Short-container-title:Thromb Haemost

Author:

Herrmann Stefan-Martin¹,Poirier Odette¹,Marques-Vidal Pedro²,Evans Alun³,Arveiler Dominique⁴,Luc Gerald⁵,Emmerich Joseph⁶,Cambien François¹

Affiliation:

1. The Institut National de la Santé et de la Recherche Médicale (Inserm) SC7, Paris

2. Monica Project Toulouse, France

3. Monica Project Belfast, Northern Ireland, UK

4. Monica Project Strasbourg, Paris, France

5. Monica Project Lille, Paris, France

6. Hôpital Broussais, Paris, France

Abstract

SummaryThe GPIIb/IIIa receptor complex may contribute to acute coronary syndromes by mediating platelet aggregation. The Leu33/Pro polymorphism (PlAl/PlA2) of the GPIIIa has recently been shown to be associated with CHD in a small case-control study. We have investigated this polymorphism in a large multicenter study of patients with myocardial infarction and controls and found no difference in the distribution of allele and genotype frequencies between cases and controls.

Publisher

Georg Thieme Verlag KG

Subject

Hematology

Link

http://www.thieme-connect.de/products/ejournals/pdf/10.1055/s-0038-1656134.pdf

Cited by 73 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Myocardial infarction before and after the age of 45: Possible role of platelet receptor polymorphisms;Revista Portuguesa de Cardiologia;2018-09

2. Myocardial infarction before and after the age of 45: Possible role of platelet receptor polymorphisms;Revista Portuguesa de Cardiologia (English Edition);2018-09

3. The PlA1/A2 Polymorphism of Glycoprotein IIIa as a Risk Factor for Myocardial Infarction: A Meta-Analysis;PLoS ONE;2014-07-02

4. Platelet glycoprotein IIIA PIA1/A2 polymorphism in young patients with ST elevation myocardial infarction and idiopathic ischemic stroke;Molecular and Cellular Biochemistry;2013-09-05

5. Platelet Genomics;Platelets;2013