A Collaborative Calibration Study of Reference Materials for Thromboplastins-Reference-Cited by-同舟云学术

A Collaborative Calibration Study of Reference Materials for Thromboplastins

Published:1983 Issue:03 Volume:50 Page:712-717
ISSN:0340-6245
Container-title:Thrombosis and Haemostasis
language:en
Short-container-title:Thromb Haemost

Author:

Hermans J¹,van den Besselaar A M H P²,Loeliger E A²,van der Velde E A¹

Affiliation:

1. The Department of Medical Statistics, Medical Faculty, University of Leiden, The Netherlands

2. The Division of Haemostasis and Thrombosis Research, Haematology Section, Department of Medicine, University Hospital, Leiden, The Netherlands

Abstract

SummaryIn a collaborative study of ten laboratories performed mainly within the framework of the BCR (the European Community Bureau of Reference), five thromboplastins were calibrated against the WHO (World Health Organisation) primary international reference preparation 67/40. Of these five thromboplastins, three were BCR reference materials (BCT/099, OBT/79 and RBT/79) and two were WHO secondary international reference preparations (68/434 and 70/178). Human brain tissue type is represented by 67/40 and BCT/099; bovine type by 68/434 and OBT/79, and rabbit type by 70/178 and RBT/79.The calibration relations are expressed in terms of a linear relationship between the logarithms of the prothrombin times, measured in seconds.

Publisher

Georg Thieme Verlag KG

Subject

Hematology

Link

http://www.thieme-connect.de/products/ejournals/pdf/10.1055/s-0038-1665293.pdf

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