Synoviorthesis Versus Synovectomy in the Treatment of Recurrent Haemophilic Haemarthrosis: Long-Term Evaluation

Author:

Gamba G1,Grignani G1,Ascari E2

Affiliation:

1. The Department of Clinical Medicine “Adolfo Ferrata”, University of Pavia, Italy, and Haemophilia Center, San Matteo Hospital, Pavia, Italy

2. Department of Medical Pathology, University of Pavia, Italy

Abstract

SummaryThe authors report a long-term evaluation of the effects of chemical and surgical synovectomies performed in two groups of patients which were comparable as regards number of haemarthrosis per year and joint mobility. The results obtained indicated that both synovectomy and synoviorthesis were effective in reducing the bleeding episodes; however, while synovectomy stopped almost completely the recurrence of haemarthrosis, synoviorthesis in 3 patients younger than 12 years did not modify it and in one case it even increased the bleeding tendency.Moreover, the occurrence of arthritic pain was observed in 6 knees treated by synoviorthesis and only in 3 knees treated by synovectomy. Finally, the joint function was significantly reduced in the synoviorthesis group as compared to the synovectomy group.In conclusion, synovectomy gave better results than synoviorthesis but the latter treatment has a number of economical and technical advantages and should therefore be considered in patients older than 12 years of age with good joint function and without evident radiological changes, in whom fulldose replacement therapy has had no effect on the recurrence of haemarthrosis.

Publisher

Georg Thieme Verlag KG

Subject

Hematology

Cited by 19 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

1. Surgery for chronic arthropathy in people with haemophilia;Cochrane Database of Systematic Reviews;2022-11-30

2. Osteochondrosis or Epiphysitis and Other Miscellaneous Affections;Campbell's Operative Orthopaedics;2013

3. POST-OPERATIVE COMPLICATIONS AND JOINT FUNCTION AFTER KNEE SYNOVECTOMY IN HAEMOPHILIACS;British Journal of Haematology;2008-07-07

4. Hematologic Disorders;Tachdjian's Pediatric Orthopaedics;2008

5. Osteochondrosis or Epiphysitis and Other Miscellaneous Affections;Campbell's Operative Orthopaedics;2008

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