Long-Term Clinical Investigation of the Hepatobiliary Agents: 99mTc- HIDA and 99mTC-p-Butyl-IDA

Author:

AI-Hilli A. M.,Dahir N. D.,Al-Hissoni M. S.,Jasim M. N.,Miran K. M.,Amira H.,Agha N. H.

Abstract

The organ distribution data for the two hepatobiliary agents HIDA and p-butyl- IDA in mice showed substantial differences in the extent and rate of hepatobiliary clearance of radioactivity. 99mTc-HIDA and 99mTc-p-butyl-IDA were used in computer assisted serial hepatobiliary scintigraphy. In normal subjects, the data of dynamic studies showed that the kidneys were no longer seen after 2.5 min with p-butyl-IDA. Liver radioactivity decreased significantly after 10 min with HIDA compared to 35 min with p-butyl-IDA. The gall bladder was always visualized at the 10-12th min and the 25-30th min with HIDA and p-butyl-IDA respectively. 99mTc-HIDA provided superior hepatic duct images.

Publisher

Georg Thieme Verlag KG

Subject

Radiology Nuclear Medicine and imaging,General Medicine

Cited by 1 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

1. Indirect spectrophotometric determination of BIDA, DISIDA, DTPA and MDP in labelled compounds;International Journal of Radiation Applications and Instrumentation. Part A. Applied Radiation and Isotopes;1989-01

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