Staging Cancer: TNM Literature 1963—1982

Abstract

The prognosis of a malignant tumour largely depends on the stage of the disease at the beginning of a specific therapy; statistics of therapy are comparable only if they show the distribution of the cases to the different stages of the disease. Aiming to improve the comparability of the data and findings acquired from the cancer patient, the UICC has, for more than 30 years, been endeavouring to develop uniform rules for acquiring the stage of the disease and the degree of spread with malignant tumours. For this purpose, UICC has developed the TNM system which makes it possible to state accurately and in a reproduceable form the stage of the primary tumour (T) and the regional lymphatic nodes (N) as well as the possible existence of metastases (M). The third edition of the TNM rules appeared in English in 1978, in the following years in numerous other languages. Today the TNM system represents the only basis for the documentation of the cancer stage which has been introduced worldwide. However, it is by no means »complete«; for some forms of cancer proposals for TNM classification are still outstanding (e.g., tumours of the pancreas, the central nervous system, the bones and the soft tissues). Moreover, malignant lymphomas cannot be classified according to the principles of TNM. Here the so-called »Ann Arbor Classification« from the year 1971 is recommended.The UICC has called upon its national committees to check the classification proposals available so far as to their usefulness and practicability. Corresponding field studies are under way in several countries. This bibliography covers a section of the TNM literature of the last 20 years. From a total number of about 2,000 publications, applying the TNM system, we selected 300 which discuss the system critically and, in most instances, make suggestions for its improvement. The first part of the bibliography contains an alphabetically arranged list of the titles according to authors’ names; the second part differentiates the tumors dealt with by their site.We thank Mrs. L. Blumenthal, Mrs. I. Schäfer and Mrs. U. Wolber for their cooperation in setting up this bibliography.