Diagnostic value Of Ethanol Gelation Test (EGT) And Fibrin- (OGEN) Degradation Products (FDP) In Suspected Deep Vein Thrombosis (DVT), Correlated To The 125-1-Fibrinogen Uptake Test (FUT)

Abstract

The study was performed in order to investigate the correlation between EGT, respectively FDP, and a positive FUT (FUT+), confirmed by venography. Control groups: patients 1) with a negative FUT (FOT−) in spite of DVT, 2) without DVT, because a negative venography also implies FUT−. Accordingly, FUT was not accomplished in this group.The material consisted of 41 patients with clinically suspected DVT; 20 with and 21 without DVT. Of the patients with DVT, 9 were definitely FUT+ and 11 definitely FUT−.EGT was applied for detection of soluble fibrin, Thrombo- Wellcotest for FDP and the Chi-squared test for statistical analysis. Blood specimens were analysed 0-1 days before isotope injection in patients with DVT, or 0-2 days before a negative venography.Conclusions: In this material, 1) Concurrently abnormal EGT and FDP was specific for the FUT+ patients. 2) On the other hand, a positive FUT could be excluded when both parameters were normal. 3) In patients with DVT, a positive EGT was found only in the FUT+ patients. (P values in the table refers to comparison with the FUT+ group).