Vitamin K Dependent Proteins in Fetal Hemostasis at Mid Trimester of Pregnancy-Reference-Cited by-同舟云学术

Vitamin K Dependent Proteins in Fetal Hemostasis at Mid Trimester of Pregnancy

Published:1985 Issue:03 Volume:53 Page:401-403
ISSN:0340-6245
Container-title:Thrombosis and Haemostasis
language:en
Short-container-title:Thromb Haemost

Author:

Forestier F¹,Daffos F¹,Rainaut M¹,Solé Y¹,Amiral J²

Affiliation:

1. The Centre de Diagnostic Prénatal et de Foetologie, Hôpital Notre Dame de Bon-Secours, Paris, France

2. The Laboratoire STAGO, Franconville, France

Abstract

SummaryThe vitamin K dependent coagulation factor activities were measured in 63 normal human fetuses from 19 to 28 weeks of pregnancy. These activities were included between 9 to 28 percent of normal adult levels.Prothrombin antigen, factor IX antigen and protein C were also measured. There is a good correlation between prothrombin procoagulant activity and antigenicity, suggesting that low level of these vitamin K dependent proteins in fetuses is probably a consequence of liver immaturity.

Publisher

Georg Thieme Verlag KG

Subject

Hematology

Link

http://www.thieme-connect.de/products/ejournals/pdf/10.1055/s-0038-1661323.pdf

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