Clinical Problem Solving and Using New Paths in the Laboratory: Learning from Case Studies

Author:

Lämmle Bernhard123ORCID

Affiliation:

1. Department of Hematology and Central Hematology Laboratory, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland

2. Center for Thrombosis and Hemostasis, University Medical Center, Johannes Gutenberg University, Mainz, Germany

3. Haemostasis Research Unit, University College London, London, United Kingdom

Abstract

AbstractThree selected casuistic studies of individual patient problems from my long-standing professional experience are presented. I intend to highlight the potential contribution of case studies, including new approaches of laboratory investigation, for the advancement of pathophysiological knowledge and would encourage to “rehabilitate” the low academic profile generally attributed to “case reports.”

Publisher

Georg Thieme Verlag KG

Subject

Hematology

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4. Genetic predisposition to bleeding during oral anticoagulant therapy: evidence for common founder mutations (FIXVal-10 and FIXThr-10) and an independent CpG hotspot mutation (FIXThr-10);J Oldenburg;Thromb Haemost,2001

5. Should patients starting anticoagulant therapy be screened for missense mutations at Ala-10 in the factor IX propeptide?;J Peters;Br J Haematol,1997

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