Affiliation:
1. Department of Internal Medicine, Hebei Medical University,
Shijiazhuang, Hebei, China
2. Endocrinology Department, Hebei General Hospital, Shijiazhuang, Hebei,
China
Abstract
AbstractThe aim of this study was to explore the association of the triglyceride to
high-density lipoprotein ratio (TG/HDL) and the visceral adiposity
index (VAI) with metabolic syndrome (Mets) in high-risk populations of
diabetic patients. Patients were recruited from the Endocrinology Clinic of
Hebei General Hospital from April 2018 to April 2019,according to the
“Guidelines for the Prevention and Treatment of Type 2 Diabetes in
China (2017 Edition)”. A total of 824 patients participated in the
study. The association between TG/HDL or VAI and Mets in these
patients was assessed using a multivariate logistic regression model.
Receiver operating characteristic (ROC) curve analysis was used to evaluate
the ability of TG/HDL and VAI to predict Mets in the diabetic
susceptible population. The prevalence of Mets gradually increased in males
and females with advancing tertiles of TG/HDL or VAI. After
adjusting for the relevant risk factors, TG/HDL and VAI were
positively correlated with Mets in men and women. Both of them showed a
better the area under the ROC curve (AUC) for Mets in females than body mass
index, waist circumference, TG and homeostatic model assessment of insulin
resistance. In females, the cut-off point of 1.67 for VAI showed a higher
accuracy for Mets (sensitivity 0.756, specificity 0.705, Youden index
0.461), the same relationship not significant in men. TG/HDL and VAI
provide a high predictive value for Mets in a diabetic susceptible
population, especially in females.
Subject
Biochemistry, medical,Clinical Biochemistry,Endocrinology,Biochemistry,General Medicine,Endocrinology, Diabetes and Metabolism
Cited by
6 articles.
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