Affiliation:
1. Academy of Scientific and Innovative Research (AcSIR)
2. Department of Organic Synthesis and Process Chemistry, CSIR-Indian Institute of Chemical Technology
Abstract
AbstractAn efficient diastereoselective synthesis of 1′,4′-dihydro-2′H-spiro[indoline-3,3′-quinolin]-2-one derivatives was achieved using catalytic amount of l-proline. The key reactions involved in the present tandem reaction are aza-Michael addition and aldol reaction. This atom economic reaction proceeded under mild conditions with a broad substrate scope and excellent diastereoselectivity in good to excellent yields.
Subject
Organic Chemistry,Catalysis
Cited by
1 articles.
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