A Convenient Procedure for Sonogashira Reactions Using Propyne-Reference-Cited by-同舟云学术

A Convenient Procedure for Sonogashira Reactions Using Propyne

Published:2021-09-20 Issue:03 Volume:54 Page:655-657
ISSN:0039-7881
Container-title:Synthesis
language:en
Short-container-title:Synthesis

Author:

Kraus George A.,Alterman Joshua L.

Abstract

AbstractA modified Sonogashira coupling of aryl iodides and propyne was achieved using only two equivalents of propyne in THF from –78 °C to room temperature.

Funder

U.S. Department of Energy

Publisher

Georg Thieme Verlag KG

Subject

Organic Chemistry,Catalysis

Link

http://www.thieme-connect.de/products/ejournals/pdf/10.1055/a-1648-7074.pdf

Reference14 articles.

1. The Sonogashira Reaction: A Booming Methodology in Synthetic Organic Chemistry

2. Potential Safety Hazards Associated with Pd-Catalyzed Cross-Coupling Reactions

3. CsF-Mediated in Situ Desilylation of TMS-Alkynes for Sonogashira Reaction

4. In Situ Generation of 1-Propyne: A Useful Introduction of 1-Propyne on Unsaturated Halogenated Compounds through the Sonogashira Reaction

5. Iridium-Catalyzed Intramolecular Methoxy C−H Addition to Carbon-Carbon Triple Bonds: Direct Synthesis of 3-Substituted Benzofurans from o -Methoxyphenylalkynes

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