Recent Advances in Chiral Aldehyde Catalysis for Asymmetric Functionalization of Amines

Author:

Wen WeiORCID,Guo Qi-Xiang

Abstract

AbstractAsymmetric functionalization of amines and their derivatives is of great significance in synthetic chemistry and is widely used in the preparation of natural products and pharmaceuticals. In recent years, chiral aldehyde catalysis has emerged as a well-established and recognized tool, providing excellent catalytic activation and stereoselective control in asymmetric reactions of N-unprotected amino acid esters and amino acid ester analogues. In this short review, recent advances in enantioselective aldehyde catalysis, including chiral aldehydes as organocatalysts and co-catalysis combined with transition metals, will be summarized. Lastly, continued development of enantioselective aldehyde catalysis is prospected in the future.1 Introduction2 Chiral Aldehyde Catalysis for Tethering Strategy3 Chiral Aldehyde Catalysis for Imine Activation4 Chiral Aldehyde/Transition Metal Cooperative Catalysis5 Conclusion

Funder

Innovation Research 2035 Pilot Plan of Southwest University

National Natural Science Foundation of China

Fundamental Research Funds for the Central Universities

Natural Science Foundation of Chongqing

Publisher

Georg Thieme Verlag KG

Subject

Organic Chemistry,Catalysis

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3