Affiliation:
1. Institute for Molecular Science (IMS) and JST-ACCEL
Abstract
An aqueous continuous-flow reaction system is developed for the palladium-catalyzed hydroxycarbonylation of aryl halides. Flow hydroxycarbonylation of aryl halides in aqueous solution proceeds efficiently in a flow reactor containing a palladium–diphenylphosphine complex immobilized on an amphiphilic polystyrene–poly(ethylene glycol) resin to give the corresponding benzoic acids in excellent yields.
Funder
Japan Science and Technology Agency
Japan Society for the Promotion of Science
Cited by
10 articles.
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