Hollow Fiber Oxygenator Composition Has a Significant Impact on Failure Rates in Neonates on Extracorporeal Membrane Oxygenation: A Retrospective Analysis-Reference-Cited by-同舟云学术

Hollow Fiber Oxygenator Composition Has a Significant Impact on Failure Rates in Neonates on Extracorporeal Membrane Oxygenation: A Retrospective Analysis

Published:2017-03-07 Issue:01 Volume:07 Page:007-013
ISSN:2146-4618
Container-title:Journal of Pediatric Intensive Care
language:en
Short-container-title:J Pediatr Intensive Care

Author:

Bernard Philip¹,Skinner Sean²,Bhandary Prasad³,Ruzic Ana²,Bacon Matthew¹,Ballard Hubert³,Daniel John³

Affiliation:

1. Division of Pediatric Critical Care, Department of Pediatrics, University of Kentucky, Lexington, Kentucky, United States

2. Division of Pediatric Surgery, Department of Surgery, University of Kentucky, Lexington, Kentucky, United States

3. Division of Neonatology, Department of Pediatrics, University of Kentucky, Lexington, Kentucky, United States

Abstract

AbstractIn extracorporeal life support (ECLS), there are two main types of oxygenators in clinical use for neonates: polymethylpentene (PMP) hollow fiber and polypropylene (PP) hollow fiber. A retrospective study was performed on neonates (n = 44) who had undergone ECLS for noncardiac indications from 2009 to 2015. Between the two groups (PMP n = 21, PP n = 23), the PP oxygenators failed 91% of the time, whereas the PMP oxygenators failed 43% of the time (p < 0.05). Analysis suggests PMP oxygenators are less prone to failure than PP oxygenators, and they require fewer number of oxygenator changes during a neonatal ECLS.

Publisher

Georg Thieme Verlag KG

Subject

Critical Care and Intensive Care Medicine,Pediatrics, Perinatology and Child Health

Link

http://www.thieme-connect.de/products/ejournals/pdf/10.1055/s-0037-1599150.pdf

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