Affiliation:
1. School of Chemistry and Chemical Engineering, Jiangsu University
2. State Key Laboratory of the Discovery and Development of Novel Pesticide (Shenyang Sinochem Agrochemicals R&D Co. Ltd)
Abstract
A facile synthesis of novel dispiroheterocycles has been developed through one-pot [3+2] cycloaddition between isatins, amino acids, and aurones. Thirty different dispiroheterocycles were synthesized eusing this method which features mild conditions, convenient operation, and high efficacy. Evaluation of the bioactivity of these dispiroheterocyclic products revealed antiviral activity against tobacco mosaic virus (TMV).
Funder
National Natural Science Foundation of China
Jiangsu University
Subject
Organic Chemistry,Catalysis
Cited by
16 articles.
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