Diastereoselective Synthesis of Cyclic sp3-Enriched cis-β-Alkoxysulfonyl Chlorides-Reference-Cited by-同舟云学术

Diastereoselective Synthesis of Cyclic sp3-Enriched cis-β-Alkoxysulfonyl Chlorides

Published:2018-10-22 Issue:04 Volume:51 Page:848-858
ISSN:0039-7881
Container-title:Synthesis
language:en
Short-container-title:Synthesis

Author:

Grygorenko Oleksandr¹²^ORCID,Sokolov Andriy¹²,Golovach Sergey¹,Kozlinsky Ihor¹³,Dolia Krystyna¹³,Tolmachev Andrey¹²,Kuchkovska Yuliya¹²

Affiliation:

1. Enamine Ltd.

2. National Taras Shevchenko University of Kyiv

3. National Technical University of Ukraine ‘Igor Sikorsky Kyiv Polytechnic Institute’

Abstract

A three-step synthesis of β-alkoxy-substituted alicyclic sulfonyl chlorides from cyclic alkenes and alcohols is reported. The scope of the method was studied for a range of the substrates with various steric and electronic properties. The title compounds were obtained on a hundred-gram scale in up to 52% overall yield scale as single cis-diastereomers.

Publisher

Georg Thieme Verlag KG

Subject

Organic Chemistry,Catalysis

Link

http://www.thieme-connect.de/products/ejournals/pdf/10.1055/s-0037-1611277.pdf

Cited by 4 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Telluronium‐Catalyzed Halogenation Reactions: Chalcogen‐Bond Activation of N‐Halosuccinimides and Catalysis;Chemistry – A European Journal;2024-07-09

2. A Close-up Look at the Chemical Space of Commercially Available Building Blocks for Medicinal Chemistry;Journal of Chemical Information and Modeling;2021-12-20

3. Synthesis and reactions of ω-CF3O-substituted aliphatic sulfonyl chlorides;Journal of Fluorine Chemistry;2021-06

4. Synthesis of sp3-Enriched β-Fluoro Sulfonyl Chlorides;Synthesis;2020-12-15