Colloidal Chromic Phosphate: its Biological Behaviour

Abstract

SummaryThe distribution within the body of various types of colloidal chromic phosphate (51Cr32PO4) at different times after intravenous and intraperitoneal injection has been studied. The possible hydrolysis “in situ” of the chromic phosphate was determined by studying the ratio β-activity / γ-activity. Similar studies have been performed with the different fractions of bone. The true colloidal chromic phosphate — in contrast to the particulated one — migrates in 50% of the cases to the liver 24 h after intraperitoneal administration. This behavior indicates the usefulness of this type of preparation for postoperative tumor prophylaxis.